PROTECTIVE IMMUNE RESPONSE TO EXPERIMENTAL INFECTION WITH SARCOCYSTIS NEURONA IN C57BL/6 MICE
نویسندگان
چکیده
منابع مشابه
Response of Horses Exposed to Sarcocystis neurona When Monitored Biweekly
The incubation period of equine protozoal myeloencephalitis may be highly variable and horses may not always develop clinical signs after confirmed exposure. Horses appear to require other risk factors in addition to exposure to Sarcocystis neurona in order to develop clinical signs. Repeated exposures may be protective. Authors’ addresses: College of Veterinary Medicine, Depts. of Veterinary P...
متن کاملEffects of Experimental Sarcocystis neurona-Induced Infection on Immunity in an Equine Model
Sarcocystis neurona is the most common cause of Equine Protozoal Myeloencephalitis (EPM), affecting 0.5-1% horses in the United States during their lifetimes. The objective of this study was to evaluate the equine immune responses in an experimentally induced Sarcocystis neurona infection model. Neurologic parameters were recorded prior to and throughout the 70-day study by blinded investigator...
متن کاملPathology of sarcocystis neurona in interferon-gamma gene knockout mice.
Pathologic changes were studied in 27 interferon-gamma gene knockout mice 34-54 days after being fed graded doses of Sarcocystis neurona sporocysts derived from a naturally infected opossum. The target tissue for S. neurona infection was the central nervous system. Characteristic histopathologic changes present in all mice consisted of an inflammatory infiltrate consisting of mostly neutrophils...
متن کاملSerologic responses of cats against experimental Sarcocystis neurona infections.
Sarcocystis neurona is the most important cause of a neurologic disease of horses, equine protozoal myeloencephalitis (EPM). Cats and other carnivores can act as its intermediate hosts and horses are aberrant hosts. Little is known of the sero-epidemiology of S. neurona infections in cats. In the present study, antibodies to S. neurona were evaluated by the S. neurona agglutination test (SAT). ...
متن کاملImmune response to infection with Salmonella typhimurium in mice.
Infection of mice with Salmonella typhimurium results in systemic infection and a disease similar to that seen in humans after infection with S. typhi. The innate immune system can restrict replication of S. typhimurium to a certain degree, but for effective control and eradication of bacteria, acquired immunity is essential. Salmonella infection induces the generation of specific CD4+ and CD8+...
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ژورنال
عنوان ژورنال: Journal of Parasitology
سال: 2003
ISSN: 0022-3395,1937-2345
DOI: 10.1645/ge-67r